Description

2,3-Didehydro-7-Ethyl-7α-Hydroxy-4,8-Cyclo-20,21-Dinoraspidospermidine-3-Carboxylic Acid Methyl Ester is a complex, high-purity alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical advanced intermediate for the development of novel therapeutic agents, particularly those targeting neurological and oncological pathways. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex alkaloid-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new molecules with potential biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Employed in advanced synthetic methodologies, including cyclization and functional group transformation reactions, due to its intricate polycyclic structure.
• Biochemical Research: Investigated for its interaction with biological targets, such as ion channels or enzymes, in preclinical studies.

Basic Information

Product Name	2,3-Didehydro-7-Ethyl-7α-Hydroxy-4,8-Cyclo-20,21-Dinoraspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	55855-14-6
Molecular Formula	C22H28N2O3
Molecular Weight	368.47 g/mol
Synonyms	Methyl 2,3-didehydro-7-ethyl-7α-hydroxy-4,8-cyclo-20,21-dinoraspidospermidine-3-carboxylate; 7-Ethyl-7α-hydroxy-4,8-cyclo-aspidospermidine derivative; Aspidospermidine-3-carboxylic acid, 2,3-didehydro-7-ethyl-7α-hydroxy-4,8-cyclo-20,21-dinor-, methyl ester; Dinoraspidospermidine methyl ester derivative; 55855-14-6; Methyl ester of 2,3-didehydro-7-ethyl-7α-hydroxy-4,8-cyclo-20,21-dinoraspidospermidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements or compendial standards (e.g., for use as a reference material).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive and/or hygroscopic; handling under an inert atmosphere is recommended for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.