Description

(2β,3β,5α,12β,19α)-Aspidospermidine-3-Carboxylic Acid Methyl Ester is a high-purity, specialized indole alkaloid derivative with a defined stereochemistry. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold in organic synthesis for medicinal chemistry research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise, high-quality building blocks for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex bioactive molecules and potential drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis targeting various biological pathways.
• Alkaloid Chemistry Studies: Serves as a reference standard and starting material for the semi-synthesis of other Aspidosperma-type alkaloids.
• Academic & R&D Laboratories: Employed in methodological development for asymmetric synthesis and natural product synthesis projects.
• Biochemical Tool Compound: Potential use in probing biological mechanisms due to its specific interaction with certain enzyme or receptor families.

Basic Information

Product Name	(2β,3β,5α,12β,19α)-Aspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	55781-30-1
Molecular Formula	C21H26N2O2
Molecular Weight	338.45 g/mol
Synonyms	Methyl (2β,3β,5α,12β,19α)-aspidospermidine-3-carboxylate; Aspidospermidine-3-carboxylic acid methyl ester; 19αH-Aspidospermidine-3-carboxylic acid, methyl ester; 3-Carbomethoxyaspidospermidine; (2β,3β,5α,12β,19α)-3-Carbomethoxyaspidospermidine; Methyl 3β-carboxyaspidospermidate
EINECS	Contact for details

Quality Control

Our production of (2β,3β,5α,12β,19α)-Aspidospermidine-3-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.