Description

(S)-Ftorafur CAS NO 55774-30-6 is the S-enantiomer of the fluorinated pyrimidine derivative, ftorafur, a key intermediate in the development of advanced pharmaceutical agents. This compound is valued for its role as a prodrug precursor in the synthesis of targeted chemotherapeutic formulations. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel oncology treatments and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of enantiomerically pure anticancer prodrugs and active pharmaceutical ingredients (APIs).
• Oncology Research: Used in preclinical and clinical research to study the mechanism, efficacy, and metabolism of fluoropyrimidine-based therapies.
• Metabolite Studies: Employed as a reference standard in analytical laboratories for the quantification and identification of ftorafur metabolites in biological samples.
• Process Chemistry: Serves as a chiral building block in the scale-up and optimization of synthetic routes for fluorinated nucleoside analogs.
• Academic Research: Utilized in university and institutional labs for chemical biology studies and the development of new targeted drug delivery systems.

Basic Information

Product Name	(S)-Ftorafur
CAS No.	55774-30-6
Molecular Formula	C8H9FN2O3
Molecular Weight	200.17 g/mol
Synonyms	(S)-5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione; (S)-1-(Tetrahydro-2-furanyl)-5-fluorouracil; S-Ftorafur; (S)-FT; (S)-1-(Tetrahydrofuran-2-yl)-5-fluorouracil; Ftorafur S-Enantiomer; (S)-Tegafur (less common); NSC 148958 (S-form)
EINECS	Contact for details

Quality Control

Our (S)-Ftorafur is manufactured under strict quality management systems to ensure high chemical and enantiomeric purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical assay, and impurity profile. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.