Description

(3β,20α)-11,17α-Dimethoxy-18β-[[3,5-Dimethoxy-4-(sec-Butyl)Benzoyl]Oxy]Yohimban-16β-Carboxylic Acid Methyl Ester is a complex, semi-synthetic indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. Its intricate molecular structure makes it a valuable intermediate for the synthesis of novel therapeutic agents targeting the central nervous system. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly in the fields of neurology and psychiatry.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential new active pharmaceutical ingredients (APIs), especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in laboratories analyzing complex alkaloid mixtures.
• Biochemical Research: Employed in in-vitro studies to investigate interactions with specific biological receptors or enzymes due to its yohimbane-based structure.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for potential future commercial manufacturing.

Basic Information

Product Name	(3β,20α)-11,17α-Dimethoxy-18β-[[3,5-Dimethoxy-4-(sec-Butyl)Benzoyl]Oxy]Yohimban-16β-Carboxylic Acid Methyl Ester
CAS No.	55729-37-8
Molecular Formula	C37H46N2O9
Molecular Weight	662.78 g/mol
Synonyms	Methyl (3β,20α)-11,17α-dimethoxy-18β-[[3,5-dimethoxy-4-(sec-butyl)benzoyl]oxy]yohimban-16β-carboxylate; 18β-Hydroxyyohimban-16β-carboxylic acid methyl ester 18-(3,5-dimethoxy-4-sec-butylbenzoate) derivative; Rescinnamine Impurity/Intermediate; 3',4',5',11,17-Pentamethoxy-18β-(3,5-dimethoxy-4-sec-butylbenzoyloxy)-16β-methoxycarbonyl-yohimban; ST 2121 derivative; Alkaloid C-40; Yohimban-16β-carboxylic acid, 18β-[[3,5-dimethoxy-4-(1-methylpropyl)benzoyl]oxy]-11,17-dimethoxy-, methyl ester, (3β,20α)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system to ensure traceability and consistency for our global research and development clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.