Description

Dolichol-D-Glucosylmonophosphate CAS NO 55607-88-0 is a critical glycosyl carrier lipid involved in the biosynthesis of N-linked glycoproteins and glycolipids. This compound serves as an essential intermediate in the dolichol phosphate cycle, facilitating the transfer of glucose residues during oligosaccharide assembly within the endoplasmic reticulum. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, glycobiology, and pharmaceutical development for studying and producing complex glycoconjugates.

Application

• Biochemical Research: A key substrate for studying the enzymatic pathways of N-linked protein glycosylation and glycan assembly.
• Glycobiology Studies: Used in in vitro assays to investigate the function of glucosyltransferases and the dolichol cycle.
• Enzyme Characterization: Serves as a standard or reagent for characterizing the activity of enzymes like glucosylphosphoryldolichol synthase.
• Pharmaceutical Development: Employed in research targeting congenital disorders of glycosylation (CDG) and other metabolic diseases.
• Reference Standard: Used as a high-purity analytical standard for mass spectrometry and chromatography in metabolic profiling.
• Synthetic Biology: A building block in the in vitro reconstruction of glycosylation pathways for synthetic glycoprotein production.

Basic Information

Product Name	Dolichol-D-Glucosylmonophosphate
CAS No.	55607-88-0
Molecular Formula	C_(n)H_(2n)O_(9)P (Variable 'n' based on dolichol chain length)
Molecular Weight	Variable, dependent on the isoprenoid chain length of the dolichol moiety. Contact for details.
Synonyms	Dolichyl phosphate D-glucose; Dolichyl β-D-glucosyl phosphate; Glucosylphosphoryldolichol; Dolichol monophosphate glucose; UDP-Glc:Dolichol-P Glc-1-P transferase substrate; D-Glucosyl-1-phosphodolichol; Dol-P-Glc
EINECS	Contact for details

Quality Control

Our Dolichol-D-Glucosylmonophosphate is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is analyzed to confirm identity and purity using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95% (Area Percent)
Purity (TLC)	Single major spot
Solubility	Soluble in chloroform/methanol mixtures, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.