Description

Tryptoquivaline is a specialized fungal metabolite belonging to the class of diketopiperazine alkaloids, valued for its unique biological activity profile. This compound serves as a critical reference standard and research chemical in pharmacological and biochemical studies. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and academic sectors for investigating neurotoxic mechanisms and screening for bioactive compounds.

Application

• Pharmacological Research: Used as a reference standard in studies of tremorgenic mycotoxins and their effects on the central nervous system.
• Biochemical Assay Development: Serves as a key analytical standard for method validation in the detection and quantification of fungal metabolites.
• Neuroscience Studies: Employed in research models to investigate neurotoxic pathways and potential neuroprotective agents.
• Drug Discovery Screening: Acts as a bioactive compound in high-throughput screens for identifying new therapeutic targets or lead compounds.
• Mycotoxin Analysis: Essential for the calibration of analytical instrumentation (HPLC, LC-MS) in food safety and environmental testing laboratories.
• Academic Reference Material: Supplied to universities and research institutes for graduate-level studies in toxicology and natural product chemistry.

Basic Information

Product Name	Tryptoquivaline
CAS No.	55387-45-6
Molecular Formula	C27H27N5O5
Molecular Weight	501.54 g/mol
Synonyms	Tryptoquivaline; Tryptoquivaline A; (-)-Tryptoquivaline; FR-66973; FR66973; (3S,11aS)-3-[(1S)-1-(1H-Indol-3-yl)ethyl]-6,7-dimethoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H)-dione; 1,2,3,11a-Tetrahydro-3-[(1S)-1-(1H-indol-3-yl)ethyl]-6,7-dimethoxy-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H)-dione
EINECS	Contact for details

Quality Control

Our Tryptoquivaline is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and relevant analytical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.