Description

(2α,5α)-3-Methyleneaspidofractinine CAS NO 55103-49-6 is a specialized alkaloid derivative belonging to the aspidofractinine class, characterized by its unique methylene bridge at the 3-position. This compound serves as a critical advanced intermediate and a valuable reference standard in the synthesis of complex natural products and novel pharmaceutical candidates. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of complex alkaloid-based drug candidates.
• Medicinal Chemistry: Used as a building block for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry: Serves as a critical intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: High-purity material for analytical method development, validation, and quality control in laboratories.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex aspidosperma and related indole alkaloids.
• Academic Research: Valuable compound for studying alkaloid biosynthesis, chemical reactivity, and novel organic transformations.

Basic Information

Product Name	(2α,5α)-3-Methyleneaspidofractinine
CAS No.	55103-49-6
Molecular Formula	C20H24N2
Molecular Weight	292.42 g/mol
Synonyms	3-Methyleneaspidofractinine; Aspidofractinine, 3-methylene-; 3-Methylenebispidin; (2α,5α)-3-Methyleneaspidofractinine; 3-Methylene-aspidofractinine; 55103-49-6; NSC 339586
EINECS	Contact for details

Quality Control

Our (2α,5α)-3-Methyleneaspidofractinine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles ensures material traceability and reliability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be handled under an inert atmosphere for long-term storage to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.