Description

(2α,5α)-17-Methoxyaspidofractinine-3β-Carboxylic Acid Methyl Ester is a high-purity, structurally complex alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for the development of novel bioactive molecules, particularly in the exploration of central nervous system (CNS) agents and other therapeutic areas. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and the study of their structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex alkaloid-based drug candidates and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to modify the aspidofractinine core for discovering new biological activities.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in organic synthesis and natural product chemistry.
• Process Development: Serves as a model compound for scaling up synthetic routes and optimizing reaction conditions in process chemistry.

Basic Information

Product Name	(2α,5α)-17-Methoxyaspidofractinine-3β-Carboxylic Acid Methyl Ester
CAS No.	55103-43-0
Molecular Formula	C22H28N2O3
Molecular Weight	368.47 g/mol
Synonyms	17-Methoxyaspidofractinine-3-carboxylic acid methyl ester; Methyl 17-methoxyaspidofractinine-3-carboxylate; Aspidofractinine-3-carboxylic acid, 17-methoxy-, methyl ester, (2α,5α)-; 3β-Carbomethoxy-17-methoxyaspidofractinine; 17-Methoxy-3β-methoxycarbonylaspidofractinine
EINECS	Contact for details

Quality Control

Our (2α,5α)-17-Methoxyaspidofractinine-3β-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.