Description

o-Methylfagaronine is a synthetic derivative of the natural alkaloid fagaronine, representing a key intermediate in medicinal chemistry research. This compound is valued for its role in the development of novel therapeutic agents, particularly in oncology and antimicrobial research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on alkaloid-based drug discovery.

Application

• Pharmaceutical Research Intermediate: A critical building block for the synthesis of novel alkaloid derivatives with potential anticancer and antimicrobial properties.
• Biochemical Tool Compound: Used in pharmacological studies to investigate mechanisms of action related to topoisomerase inhibition and DNA intercalation.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Medicinal Chemistry Exploration: Enables structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic profiles of fagaronine analogs.
• Academic Research: Supports fundamental studies in organic synthesis and natural product chemistry at universities and research institutes.

Basic Information

Product Name	o-Methylfagaronine
CAS No.	54785-54-5
Molecular Formula	C22H19NO5
Molecular Weight	377.39 g/mol
Synonyms	2-Methylfagaronine; 3,11-Dimethoxy-2-methyl-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-13-ium-7,14-diol; Fagaronine, 2-methyl-; o-Methylfagaronin; 2-Methylfagaronin
EINECS	Contact for details

Quality Control

Our o-Methylfagaronine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support research needs with material produced to meet in-house specifications suitable for laboratory and pilot-scale use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.