Description

P'-Di-n-Acetylchitobiosyl-P(2)-Dolichylpyrophosphate is a specialized biochemical intermediate, a dolichol-linked oligosaccharide precursor essential in the biosynthesis of N-linked glycoproteins. This compound is critical for researchers and manufacturers studying or producing complex glycoproteins, as it plays a direct role in the oligosaccharyltransferase (OST) enzyme-catalyzed glycosylation pathway. It is primarily utilized in advanced biochemical research, pharmaceutical development for biologics, and the synthesis of high-value glycoconjugates where precise glycosylation is required.

Application

• Biochemical Research: A key substrate for studying the N-linked protein glycosylation pathway, enzyme kinetics of oligosaccharyltransferase (OST), and glycan assembly mechanisms.
• Pharmaceutical Development: Used in the research and production of therapeutic glycoproteins, monoclonal antibodies, and other biologics where specific glycosylation patterns impact efficacy and stability.
• Enzymology Studies: Serves as a critical reagent for assaying the activity of glycosyltransferases and other enzymes involved in the dolichol cycle.
• Glycoconjugate Synthesis: Acts as a biosynthetic building block for the chemoenzymatic synthesis of defined oligosaccharides and complex glycoconjugates.
• Cell Biology & Metabolic Labeling: Utilized in metabolic engineering and labeling studies to trace glycan biosynthesis and turnover in cellular systems.

Basic Information

Item	Detail
Product Name	P'-Di-n-Acetylchitobiosyl-P(2)-Dolichylpyrophosphate
CAS No.	54784-58-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Chitobiosyldiphosphodolichol; Dolichyl Diphosphate Chitobiose; Dolichyl Pyrophosphate N,N'-Diacetylchitobiose; Dolichyl Diphosphate N,N'-Diacetylchitobiose; P2-Dolichyl Pyrophosphate N,N'-Diacetylchitobiose; N,N'-Diacetylchitobiosyl Diphosphodolichol; Lipid-linked Oligosaccharide Precursor (LLO); Dol-PP-(GlcNAc)2
EINECS	Contact for details

Quality Control

Our P'-Di-n-Acetylchitobiosyl-P(2)-Dolichylpyrophosphate is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Quality is verified through advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store the product under an inert atmosphere (e.g., argon or nitrogen) in a desiccated environment at recommended temperatures (typically -20°C or below for long-term stability). Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	< 1.0%
Solubility	Soluble in chloroform/methanol mixtures, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.