Description

Oestriol 17Beta-(β-D-Glucuronide), Sodium Salt is a high-purity conjugated metabolite of the estrogen hormone oestriol. This compound is a critical reference standard and intermediate for analytical and research applications, offering exceptional batch-to-batch consistency. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic institutions engaged in hormone metabolism studies and assay development.

Application

• Pharmaceutical Reference Standard: For the quantitative analysis and quality control of oestriol and its metabolites in drug development and manufacturing.
• Clinical Diagnostics: As a calibrator and control in the development of immunoassays (ELISA, RIA) for measuring estrogen levels in biological samples.
• Biochemical Research: A key substrate for studying phase II drug metabolism, specifically glucuronidation pathways and enzyme kinetics.
• Metabolite Identification: Used in LC-MS and HPLC methods as a definitive standard to identify and quantify oestriol glucuronide conjugates in pharmacokinetic studies.
• Endocrinology Studies: Essential for research into estrogen biosynthesis, conjugation, excretion, and related hormonal disorders.

Basic Information

Product Name	Oestriol 17Beta-(β-D-Glucuronide), Sodium Salt
CAS No.	54677-26-8
Molecular Formula	C24H31NaO9
Molecular Weight	486.49 g/mol
Synonyms	Estriol 17β-D-Glucuronide Sodium Salt; Estratriol 17β-Glucuronide Sodium Salt; Sodium Estriol 17-Glucuronide; 16α-Hydroxyestriol 17β-Glucuronide Sodium Salt; 1,3,5(10)-Estratriene-3,16α,17β-triol 17β-D-Glucopyranosiduronic Acid Sodium Salt; Oestriol 17β-Glucuronide Sodium; NSC 113233
EINECS	Contact for details

Quality Control

Our Oestriol 17Beta-(β-D-Glucuronide), Sodium Salt is manufactured under strict quality systems to ensure high purity and reliability for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for reference materials to guarantee consistent performance and traceability in your laboratory workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.