Description

Maleyl-Coenzyme A is a crucial biochemical intermediate in the metabolism of aromatic compounds, specifically within the β-ketoadipate pathway. This high-purity coenzyme derivative is essential for research and development in enzymology and metabolic studies. It serves as a key substrate for investigating microbial degradation pathways and is vital for pharmaceutical and biotechnology laboratories focused on metabolic engineering and enzyme function analysis.

Application

• Biochemical Research: Critical substrate for studying the enzymatic mechanisms of the β-ketoadipate pathway in bacteria and fungi.
• Enzyme Assay Development: Used in the development and validation of assays for maleyl-CoA isomerase and other related enzymes.
• Metabolic Pathway Analysis: Essential for in vitro reconstruction of aromatic compound degradation pathways for metabolic engineering applications.
• Pharmaceutical R&D: Employed in research targeting metabolic disorders or exploring novel biodegradation processes for drug development.
• Academic Research: A fundamental tool in microbiology and biochemistry laboratories for teaching and advanced research into catabolic pathways.
• Biocatalyst Screening: Used as a standard in high-throughput screening for enzymes capable of transforming aromatic intermediates.

Basic Information

Product Name	Maleyl-Coenzyme A
CAS No.	54377-18-3
Molecular Formula	C₂₅H₃₈N₇O₁₉P₃S
Molecular Weight	897.66 g/mol
Synonyms	Maleyl-CoA; (2E)-But-2-enedioyl-CoA; trans-1,2-Ethenedicarboxylic acid-CoA; Maleyl-coenzyme A; Coenzyme A, S-maleyl-; Maleyl CoA; 3'-Phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-{[2-(sulfanylethyl)carbamoyl]ethyl}propyl)amino]butyl} dihydrogen diphosphate) (2E)-4-oxobut-2-enoate
EINECS	Contact for details

Quality Control

Our Maleyl-Coenzyme A is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards to guarantee product integrity and performance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Functional as substrate for maleyl-CoA isomerase

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.