Description

8-Pcpt-Cgmp, Tea CAS NO 54364-02-2 is a specialized biochemical compound, a cyclic guanosine monophosphate (cGMP) derivative, known for its role as a second messenger in cellular signal transduction. This high-purity intermediate is critical for research and development in advanced pharmaceutical synthesis and life science studies. It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and academic research institutions focusing on cardiovascular, neurological, and metabolic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutics targeting cGMP-dependent pathways.
• Biochemical Research: Used as a standard or reagent in studies of cyclic nucleotide signaling, enzyme kinetics (e.g., phosphodiesterase inhibition), and cell biology.
• Diagnostic Development: Employed in the development of assay kits and diagnostic tools for measuring cGMP levels in biological samples.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting fundamental research on cellular communication.
• Drug Discovery Screening: Utilized in high-throughput screening (HTS) platforms to identify new drug candidates that modulate the cGMP pathway.

Basic Information

Product Name	8-Pcpt-Cgmp, Tea
CAS No.	54364-02-2
Molecular Formula	C16H23N7O7P
Molecular Weight	456.37 g/mol
Synonyms	8-(4-Chlorophenylthio)guanosine-3',5'-cyclic monophosphate triethylammonium salt; 8-pCPT-cGMP, TEA salt; 8-(4-Chlorophenylthio)-cGMP TEA; 8-CPT-cGMP; cGMP analog, 8-pCPT-; Biolog cGMP analog B007; Cell-permeable cGMP analog
EINECS	Contact for details

Quality Control

Our 8-Pcpt-Cgmp, Tea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible results in sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.