Description

C18 Sphingomyelin (D18:1/18:0) is a high-purity, defined-chain sphingolipid essential for advanced biomedical research and formulation development. This compound matters as a critical building block for constructing biomimetic membranes and studying lipid raft dynamics, cell signaling, and apoptosis. It is needed by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries for applications in drug delivery systems, diagnostic assays, and high-value lipid supplements.

Application

• Biomembrane & Lipid Raft Research: Used as a key component to model and study the structure and function of cell membranes, particularly lipid rafts and signaling domains.
• Drug Delivery System Development: Incorporated into liposomal and nanoparticle formulations to enhance targeting, stability, and cellular uptake of therapeutic agents.
• Cell Biology & Signaling Studies: Essential for investigating sphingomyelinase pathways, ceramide generation, and their roles in cell cycle regulation and apoptosis.
• Diagnostic Reagent Production: Serves as a standard or raw material in the manufacture of kits for enzymatic assays and clinical diagnostics related to lipid metabolism.
• Nutraceutical & Cosmetic Formulation: Employed in high-end skincare and supplement products for its role in skin barrier function and cellular health.
• Biophysical Analysis: Used in techniques like NMR, mass spectrometry, and calorimetry as a reference standard for lipid analysis and characterization.

Basic Information

Product Name	C18 Sphingomyelin (D18:1/18:0)
CAS No.	54336-69-5
Molecular Formula	C41H83N2O6P
Molecular Weight	731.08 g/mol
Synonyms	N-(Octadecanoyl)-sphing-4-enine-1-phosphocholine; N-Stearoyl-D-erythro-sphingosylphosphorylcholine; SM(d18:1/18:0); Sphingomyelin (18:0); (2S,3R,4E)-2-Octadecanoylamino-4-octadecene-1,3-diol 1-Phosphocholine; D-erythro-Sphingosine, N-stearoyl-, 1-phosphocholine; Sphingomyelin from bovine brain (major component); LIPOID SM 80
EINECS	Contact for details

Quality Control

Our C18 Sphingomyelin is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and cGMP-guided applications. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.