Description

Dipeptidylpeptidase Iv CAS NO 54249-88-6 is a highly specific serine protease enzyme that plays a critical role in the regulation of incretin hormones. This enzyme is essential for research and development in metabolic disease studies, particularly for investigating type 2 diabetes pathways. It is a key reagent for pharmaceutical companies, academic research institutions, and diagnostic manufacturers focused on endocrinology and drug discovery.

Application

• Biochemical Research: Used as a critical tool for studying the mechanism of action of incretin hormones like GLP-1 and GIP.
• Drug Discovery & Screening: Essential for the in vitro screening and characterization of DPP-4 inhibitor candidates for anti-diabetic therapeutics.
• Diagnostic Kit Development: Serves as a key component in the development of enzymatic assays and diagnostic kits for metabolic disorder research.
• Enzymology Studies: Employed in kinetic studies to understand substrate specificity and enzyme inhibition kinetics.
• Pharmaceutical Reference Standard: Used as a reference material for quality control and assay validation in pharmaceutical manufacturing.

Basic Information

Product Name	Dipeptidylpeptidase Iv
CAS No.	54249-88-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	DPP-4; Dipeptidyl Peptidase 4; DPP-IV; CD26; Adenosine Deaminase Complexing Protein 2; T-Cell Activation Antigen CD26; Glycoprotein GP110; Xaa-Pro-Dipeptidyl-Aminopeptidase; EC 3.4.14.5
EINECS	Contact for details

Quality Control

Our Dipeptidylpeptidase IV is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high enzymatic activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, specific activity, and stability data, meeting the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain activity. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to standard
Specific Activity	> 10 U/mg protein
Protein Content (Biuret)	> 90%
Purity (SDS-PAGE)	> 95%
Solubility	Soluble in water or buffer
Loss on Drying	< 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.