Description

(R)-Salsolidine is a chiral tetrahydroisoquinoline alkaloid of significant interest in organic synthesis and pharmaceutical research. Its defined stereochemistry makes it a valuable building block for the development of novel bioactive compounds and chiral catalysts. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to incorporate a specific enantiomeric scaffold into their products.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential central nervous system (CNS) active agents and other therapeutic molecules.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce enantioselectivity.
• Natural Product Research: Used as a reference standard and starting material for the synthesis of complex natural alkaloids and their analogs.
• Agrochemical Development: Serves as a scaffold for creating novel chiral pesticides and plant growth regulators with enhanced activity.
• Chemical Biology: Utilized in probe and tool compound development for studying biological pathways and receptor interactions.
• Academic & Industrial R&D: Fundamental building block for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-Salsolidine
CAS No.	54193-08-7
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	(R)-6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methylisoquinoline; (R)-1-Methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; (R)-Salsolidin; Dextro-Salsolidine; (R)-N-Methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; (R)-N-Methylsalsolidine
EINECS	Contact for details

Quality Control

Our (R)-Salsolidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including HPLC for chemical purity and chiral analysis to confirm enantiomeric excess. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific tests is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.