Description

(S)(-)-1-Methyl-2-Propynylamine is a chiral amine building block of significant importance in asymmetric synthesis. This compound matters because its propargylic amine structure and defined stereochemistry make it a valuable precursor for the development of pharmaceuticals, agrochemicals, and advanced materials. Industries that require enantiomerically pure intermediates, such as pharmaceutical R&D, fine chemical manufacturing, and catalyst design, are the primary users of this specialty chemical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of neurologically active compounds and enzyme inhibitors.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations in fine chemical synthesis.
• Agrochemical Research: Serves as a building block for novel, chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high enantiomeric purity.
• Material Science: A potential monomer or modifier in the synthesis of specialty polymers with unique optical or mechanical properties.

Basic Information

Product Name	(S)(-)-1-Methyl-2-Propynylamine
CAS No.	54164-69-1
Molecular Formula	C₄H₇N
Molecular Weight	69.11 g/mol
Synonyms	(S)-1-Methylprop-2-yn-1-amine; (S)-2-Propyn-1-amine, 1-methyl-; (S)-(-)-1-Methyl-2-propynylamine; (S)-1-Amino-2-butyne; (S)-2-Butyn-1-amine; (S)-1-Methylpropargylamine; (S)-(-)-1-Methylpropargylamine; (S)-1-Methyl-2-propyn-1-amine
EINECS	Contact for details

Quality Control

Our (S)(-)-1-Methyl-2-Propynylamine is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, identity confirmation by IR and NMR spectroscopy, and purity assessment. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.