Description

(R)-3-Amino-3-(3,4-Dimethoxy-Phenyl)-Propionic Acid CAS NO 54160-63-3 is a chiral, non-proteinogenic amino acid derivative featuring a dimethoxyphenyl substituent. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting the central nervous system. It is essential for research and production in pharmaceutical chemistry, enabling the development of enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of advanced drug candidates, especially in neurological and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or resolving agent in the preparation of enantiomerically pure compounds.
• Peptidomimetics Research: Incorporated into peptide analogs to study structure-activity relationships and enhance metabolic stability.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme mechanisms and receptor interactions.
• Catalyst Ligand Precursor: Serves as a precursor for ligands used in asymmetric catalysis.
• Academic & Industrial R&D: Fundamental research in organic and medicinal chemistry for novel compound libraries.

Basic Information

Item	Detail
Product Name	(R)-3-Amino-3-(3,4-Dimethoxy-Phenyl)-Propionic Acid
CAS No.	54160-63-3
Molecular Formula	C11H15NO4
Molecular Weight	225.24 g/mol
Synonyms	(R)-3-Amino-3-(3,4-dimethoxyphenyl)propanoic acid; (R)-3-(3,4-Dimethoxyphenyl)-3-aminopropionic acid; (R)-3-Amino-3-(3,4-dimethoxyphenyl)propionic acid; D-3-Amino-3-(3,4-dimethoxyphenyl)propionic acid; (R)-β-Amino-3,4-dimethoxyhydrocinnamic acid; (3R)-3-Amino-3-(3,4-dimethoxyphenyl)propanoic acid; (R)-3,4-Dimethoxy-β-phenyl-β-alanine
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-3-(3,4-Dimethoxy-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) documenting identity, purity, and chiral excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.