Description

2,3,10,11-Tetrahydroxyberbine is a naturally occurring isoquinoline alkaloid derivative, recognized for its distinct polyhydroxylated berbine skeleton. This compound is of significant interest in advanced research and development due to its complex structure and potential as a key synthetic intermediate or reference standard. It is primarily sought by professionals in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for applications in medicinal chemistry, analytical method development, and biochemical studies.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and study of novel bioactive compounds.
• Medicinal Chemistry: Used as a scaffold or building block for exploring structure-activity relationships (SAR) in drug discovery programs.
• Analytical Chemistry: Employed as a high-purity certified reference material (CRM) for method validation, calibration, and quality control in HPLC, LC-MS, or NMR analysis.
• Biochemical Research: Investigated for its potential biological activities and interactions in various in vitro assay systems.
• Fine Chemical Synthesis: Utilized as a specialized intermediate for the custom synthesis of complex natural product analogs and derivatives.

Basic Information

Product Name	2,3,10,11-Tetrahydroxyberbine
CAS No.	53905-56-9
Molecular Formula	C₁₉H₂₁NO₄
Molecular Weight	327.38 g/mol
Synonyms	2,3,10,11-Tetrahydroxyberbin; Berbine-2,3,10,11-tetrol; 5,6,13,13a-Tetrahydro-2,3,10,11-tetrahydroxy-8H-dibenzo[a,g]quinolizine; Tetrahydroxyberbine
EINECS	Contact for details

Quality Control

Our 2,3,10,11-Tetrahydroxyberbine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity assessment by chromatographic techniques (HPLC). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.