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1-Palmitoyl-Sn-Glycero-3-Phosphoethanolamine CAS NO 53862-35-4
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CAS No.:53862-35-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Palmitoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity, synthetic phospholipid essential for constructing biomimetic membranes and advanced drug delivery systems. Its primary value lies in its role as a key component in liposomal formulations, where it contributes to stability and targeted delivery. This compound is critically needed by researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetics industries for developing next-generation therapeutics and high-performance nano-carriers.
Application
- Liposome and Lipid Nanoparticle (LNP) Formulation: A fundamental building block for creating stable, uniform vesicles for drug and gene delivery.
- Biomimetic Membrane Research: Used to construct model cell membranes for studying protein-lipid interactions, membrane permeability, and cellular processes.
- Cosmetic Actives Delivery: Enhances the skin penetration and stability of active ingredients in premium skincare and cosmetic products.
- Diagnostic Reagent Preparation: Serves as a component in diagnostic kits and assays that utilize membrane-based detection methods.
- Surface Modification and Coatings: Applied to modify material surfaces to improve biocompatibility for medical devices and implants.
- Biochemical Research: A critical reagent for studying phospholipid metabolism, signaling pathways, and enzyme kinetics.
Basic Information
| Product Name | 1-Palmitoyl-Sn-Glycero-3-Phosphoethanolamine |
| CAS No. | 53862-35-4 |
| Molecular Formula | C21H44NO8P |
| Molecular Weight | 469.55 g/mol |
| Synonyms | 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; L-α-Phosphatidylethanolamine (C16:0); PE(16:0/0:0); 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; Palmitoyl Lyso-phosphatidylethanolamine; Lyso-PE (16:0); sn-Glycero-3-phosphoethanolamine, 1-hexadecanoyl-; N-(1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho)ethanolamine |
| EINECS | Contact for details |
Quality Control
Our 1-Palmitoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing all specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | ≤ 10 ppm |
| Peroxide Value | ≤ 5.0 mEq/kg |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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