Description

3,4-Di-o-Acetyl-1,2-o-Isopropylidene-5-o-Tosyl-α-L-Sorbopyranse is a sophisticated, multi-functional carbohydrate derivative and a key protected intermediate in organic synthesis. This compound matters because it provides a versatile chiral scaffold for the controlled construction of complex molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily needed by research chemists and process development scientists working on nucleoside analogs, antiviral agents, and other bioactive compounds where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Glycochemistry Research: Used in the study and synthesis of complex carbohydrates (glycans) and glycoconjugates for drug discovery and biochemical tools.
• Fine Chemical Synthesis: Serves as a protected precursor for the preparation of specialty chemicals, chiral ligands, and catalysts.
• Academic & Industrial R&D: Employed in method development and exploratory chemistry to create libraries of structurally diverse compounds.
• Process Chemistry: Investigated for scalable routes to high-value, optically pure active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3,4-Di-o-Acetyl-1,2-o-Isopropylidene-5-o-Tosyl-α-L-Sorbopyranse
CAS No.	53821-66-2
Molecular Formula	C20H24O9S
Molecular Weight	440.47 g/mol
Synonyms	5-O-Tosyl-1,2-O-isopropylidene-3,4-di-O-acetyl-α-L-sorbofuranose; 1,2-O-Isopropylidene-3,4-di-O-acetyl-5-O-(p-tolylsulfonyl)-α-L-sorbofuranose; 5-O-Tosyl-1,2:3,4-di-O-isopropylidene-α-L-sorbopyranose derivative; L-Sorbose, 5-O-(4-methylbenzenesulfonate), 1,2:3,4-bis-O-(1-methylethylidene)-, diacetate; 53821-66-2; Tosyl Sorbose Derivative; Protected L-Sorbose Tosylate
EINECS	Contact for details

Quality Control

Every batch of 3,4-Di-o-Acetyl-1,2-o-Isopropylidene-5-o-Tosyl-α-L-Sorbopyranse undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with cGMP principles for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.