Description

H-Trp-Obzl Tos CAS NO 53787-20-5 is a protected tryptophan derivative, specifically the benzyl ester of tryptophan with a tosylate counterion, serving as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity, structurally defined intermediates to construct complex peptides and peptidomimetics with precision. It is primarily needed by the pharmaceutical, biotechnology, and advanced research sectors for applications in drug discovery, development of therapeutic peptides, and biochemical studies.

Application

• Peptide Synthesis Intermediate: A key protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics and bioactive compounds.
• Bioconjugation & Labeling: Serves as a precursor for introducing the tryptophan moiety into larger biomolecules or for creating fluorescent probes.
• Academic & Industrial R&D: Employed in biochemical research to study protein-protein interactions, enzyme substrates, and receptor ligands.
• Combinatorial Chemistry: A valuable building block for generating diverse chemical libraries for high-throughput screening.
• Production of Custom Peptides: Used by CROs and CDMOs for the contract manufacturing of specific peptide sequences for clients.

Basic Information

Product Name	H-Trp-Obzl Tos
CAS No.	53787-20-5
Molecular Formula	C25H24N2O5S
Molecular Weight	464.53 g/mol
Synonyms	Tryptophan benzyl ester tosylate salt; H-Tryptophan-OBzl p-toluenesulfonate; L-Tryptophan benzyl ester p-toluenesulfonate; Trp(Bzl)-OH · Tos; Benzyl L-tryptophanate 4-methylbenzenesulfonic acid salt; (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid benzyl ester 4-methylbenzenesulfonate; W-OBzl Tosylate; ZL-015 (potential research code)
EINECS	Contact for details

Quality Control

Our H-Trp-Obzl Tos is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.