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1,2-Dilauroylphosphatidylethanolamine CAS NO 53695-34-4


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CAS No.:53695-34-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dilauroylphosphatidylethanolamine is a synthetic, saturated phospholipid with a defined C12 lauroyl chain length. This high-purity lipid is critical for creating stable, well-characterized liposomal and lipid nanoparticle (LNP) formulations. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries for drug delivery, vaccine development, and as a model membrane component.

Application

  • Liposomal Drug Delivery Systems: A key structural phospholipid for formulating liposomes to encapsulate and deliver active pharmaceutical ingredients (APIs).
  • Lipid Nanoparticle (LNP) Formulations: Used as a helper or structural lipid in mRNA and siRNA delivery systems for vaccines and gene therapies.
  • Biomimetic Membrane Research: Serves as a model membrane component in biophysical studies due to its defined, saturated fatty acid chains.
  • Cosmetic Nanocarriers: Employed in the development of advanced nano-emulsions and vesicles for targeted skin delivery of cosmetic actives.
  • Diagnostic Reagents: Can be used in the preparation of stable, uniform lipid layers for biosensors and diagnostic assays.
  • Cell Culture & Transfection: Acts as a raw material for synthesizing cationic lipids used in transfection reagents.

Basic Information

Product Name 1,2-Dilauroylphosphatidylethanolamine
CAS No. 53695-34-4
Molecular Formula C31H62NO8P
Molecular Weight 607.79 g/mol
Synonyms DLPE; 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine; Dilauryphosphatidylethanolamine; Phosphatidylethanolamine, 1,2-didodecanoyl-; L-α-Phosphatidylethanolamine, dilauroyl; Dodecanoylphosphatidylethanolamine; Laurylphosphatidylethanolamine; PE(12:0/12:0)
EINECS 258-718-3

Quality Control

Our 1,2-Dilauroylphosphatidylethanolamine is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and lipid profile, to ensure it meets stringent specifications for advanced research and GMP-grade applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
1-Lauroyl-2-Hydroxy (Lyso-PE) ≤ 1.0%
Solvent Residue (GC) Meets ICH guidelines
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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