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1-Palmitoyl-2-Palmitoleoyl-Sn-Glycero-3-Phosphocholine CAS NO 53595-24-7


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CAS No.:53595-24-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Palmitoyl-2-Palmitoleoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid with a defined fatty acid composition at the sn-1 and sn-2 positions. This precise molecular structure makes it an essential component for creating advanced lipid-based delivery systems and biomimetic membranes. It is particularly valuable for researchers and formulators in the pharmaceutical, biotechnology, and advanced cosmetics industries who require consistent, well-characterized lipids for critical applications.

Application

  • Liposome & Nanoparticle Formulation: A key building block for constructing stable liposomes and lipid nanoparticles (LNPs) used in drug delivery, mRNA vaccines, and gene therapy.
  • Biomembrane Research: Used to create model membrane systems (e.g., vesicles, supported lipid bilayers) for studying membrane protein function, lipid rafts, and cell signaling mechanisms.
  • Pharmaceutical Excipient: Serves as a functional excipient in injectable and topical formulations to enhance drug solubility, stability, and bioavailability.
  • Diagnostic Reagents: Incorporated into diagnostic kits and assays that utilize membrane-based detection or signal amplification.
  • Advanced Cosmetics: Employed in high-end skincare products as a biomimetic ingredient to improve skin barrier function and delivery of active compounds.
  • Cell Culture & Cryopreservation: Used as a supplement in specialized cell culture media and as a protective agent in cryopreservation solutions.

Basic Information

Product Name 1-Palmitoyl-2-Palmitoleoyl-Sn-Glycero-3-Phosphocholine
CAS No. 53595-24-7
Molecular Formula C39H76NO8P
Molecular Weight 718.00 g/mol
Synonyms 16:0-16:1 PC; POPC (Palmitoyl Oleoyl Phosphatidylcholine) variant; 1-Hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine (16:0/16:1(9Z)); PC(16:0/16:1); Glycerophosphocholine derivative; Lipid 53595-24-7; L-α-Phosphatidylcholine, palmitoyl-palmitoleoyl
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Quality Control

Every batch of 1-Palmitoyl-2-Palmitoleoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and fatty acid profile consistency. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. For long-term storage, desiccate at -20°C. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white waxy solid or film
Identification (HPLC/MS) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Fatty Acid Composition (sn-1/sn-2) Conforms to structure (16:0 / 16:1 δ9)
Solvents (Residual) Meets ICH guidelines
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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