Description

2'-Monophosphoadenosine 5'-*Diphosphoribose Sodium is a high-purity nucleotide derivative, a key intermediate in biochemical research and synthesis. This compound is critical for studying and modulating enzymatic pathways, particularly those involving coenzyme A and nucleotide metabolism. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing novel therapeutics and diagnostic tools.

Application

• Biochemical Research: As a critical substrate or intermediate for studying enzymes like phosphoadenosine phosphosulfate (PAPS) reductases and other sulfur metabolism pathways.
• Pharmaceutical Synthesis: Serves as a sophisticated building block for the synthesis of nucleotide-based drugs, prodrugs, and active pharmaceutical ingredients (APIs).
• Enzymology Studies: Used in kinetic assays and mechanistic studies to understand cofactor utilization and enzyme inhibition/activation.
• Diagnostic Reagent Development: A potential component in the formulation of high-sensitivity assay kits for clinical diagnostics and metabolic disorder testing.
• Cell Culture & Metabolism Research: Employed in cell-based studies to investigate nucleotide salvage pathways and cellular energy states.
• Reference Standard: Used as an analytical standard in HPLC, LC-MS, and NMR for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2'-Monophosphoadenosine 5'-*Diphosphoribose Sodium
CAS No.	53595-18-9
Molecular Formula	C15H22N5O16P3Na2 (or similar salt form)
Molecular Weight	Contact for details
Synonyms	PAP (3'-Phosphoadenosine 5'-phosphate) related isomer; Adenosine 2'-monophosphate 5'-diphosphoribose sodium salt; 2'-P-ADP-ribose Na; 2'-Phosphoadenosine-5'-diphosphoribose Sodium Salt; 2'-Monophosphoadenylyl-(5'→?)-ribose diphosphate sodium; A2'p5'ppRib Na; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2'-Monophosphoadenosine 5'-*Diphosphoribose Sodium is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical applications. A Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (NMR/IR), and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.