Description

Copper-Glycyl-Glycyl-Histidine is a synthetic tripeptide complex where copper ions are chelated by the glycyl-glycyl-histidine sequence. This compound matters as a highly specific and stable model system for studying copper-binding sites in proteins and enzymes, particularly those involved in critical biological processes. Researchers and manufacturers in the fields of biochemistry, pharmaceutical development, and nutritional science need it for applications ranging from fundamental metalloprotein research to the development of novel diagnostic agents and supplements.

Application

• Biochemical Research: Serves as a standard and model compound for investigating copper transport, homeostasis, and the structure-function relationships of copper-binding sites in proteins like albumin and superoxide dismutase.
• Pharmaceutical Development: Used in the research and development of metal-based therapeutics, diagnostic imaging agents, and compounds targeting oxidative stress pathways.
• Nutritional Science: Studied as a potential source of bioavailable copper in specialized nutritional formulations and supplements due to its peptide-chelated structure.
• Analytical Chemistry: Employed as a reference standard in chromatographic (HPLC) and spectroscopic methods for quantifying copper-peptide interactions.
• Enzymology Studies: Acts as an activator or inhibitor in enzymatic studies to understand the role of copper in catalytic mechanisms.
• Cosmetic Science: Investigated for potential use in anti-aging or antioxidant skincare formulations, leveraging the biological activity of copper peptides.

Basic Information

Product Name	Copper-Glycyl-Glycyl-Histidine
CAS No.	53554-01-1
Molecular Formula	C14H20CuN8O5
Molecular Weight	444.91 g/mol
Synonyms	Copper(II)-Gly-Gly-His; Cu(GGH); Glycyl-glycyl-L-histidinato copper; Copper tripeptide complex; L-Histidine, N-[N-(N-glycylglycyl)-, copper complex; NSC 135963; Copper (II) complex of glycylglycyl-L-histidine; GGH-Cu
EINECS	Contact for details

Quality Control

Our Copper-Glycyl-Glycyl-Histidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), heavy metal content, and residual solvents. Our quality systems support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Blue to blue-green solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Copper Content	13.5 - 15.0 %
Water Content (KF)	≤ 5.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.