Description

n-Iodoacetyltyramine is a specialized biochemical reagent featuring a reactive iodoacetyl group and a phenolic hydroxyl group. This bifunctional nature makes it a valuable intermediate for site-specific conjugation and labeling, particularly in the development of targeted probes and bioconjugates. It is essential for researchers and manufacturers in the pharmaceutical and life sciences sectors engaged in advanced drug discovery, proteomics, and diagnostic assay development.

Application

• Bioconjugation Reagent: Used for the site-specific modification of peptides, proteins, and antibodies via thiol-reactive chemistry.
• Proteomics Research: Acts as a key intermediate in the synthesis of activity-based probes (ABPs) for enzyme profiling and target identification.
• Radiopharmaceutical Precursor: Serves as a versatile synthon for the development of iodine-123 or iodine-131 labeled compounds for diagnostic imaging or therapy.
• Crosslinking Agent: Employed in the preparation of affinity matrices and immobilized ligands for chromatography and biosensor applications.
• Fluorescent Probe Synthesis: A building block for creating fluorescently tagged molecules for cellular imaging and flow cytometry.
• Pharmaceutical Intermediate: Utilized in the research and development of novel therapeutic agents, including antibody-drug conjugates (ADCs).

Basic Information

Product Name	n-Iodoacetyltyramine
CAS No.	53527-07-4
Molecular Formula	C10H12INO3
Molecular Weight	305.11 g/mol
Synonyms	N-(2-(4-Hydroxyphenyl)ethyl)-2-iodoacetamide; 2-Iodo-N-[2-(4-hydroxyphenyl)ethyl]acetamide; Iodoacetyltyramine; 4-(2-((2-Iodoacetyl)amino)ethyl)phenol; Tyramine iodoacetamide; N-Iodoacetyltyramine; IAT
EINECS	Contact for details

Quality Control

Our n-Iodoacetyltyramine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.