Description

5-S-Ethyl-5-Thioribose is a specialized thiosugar derivative, a key chiral building block in organic synthesis and pharmaceutical research. Its value lies in its role as a precursor for nucleoside analogs and other bioactive molecules, enabling the development of novel therapeutic agents. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop antiviral, anticancer, or other nucleoside-based drugs.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of modified nucleosides and nucleotides for antiviral and anticancer drug discovery.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Glycobiology & Glycomics: Serves as a building block for synthesizing thio-glycosides and carbohydrate mimetics to study carbohydrate-protein interactions.
• Fine Chemical Synthesis: A versatile chiral synthon for constructing complex molecules in asymmetric synthesis and medicinal chemistry.
• Antisense Oligonucleotide Development: Potential use in creating backbone-modified oligonucleotides for therapeutic applications.
• Radiopharmaceuticals: Can be utilized as a precursor for labeling with isotopes like sulfur-35 for tracer studies.

Basic Information

Product Name	5-S-Ethyl-5-Thioribose
CAS No.	53458-56-3
Molecular Formula	C7H14O4S
Molecular Weight	194.25 g/mol
Synonyms	5-Ethylthio-5-deoxy-D-ribose; 5-Deoxy-5-ethylthio-D-ribose; 5-S-Ethyl-5-thio-D-ribose; D-Ribose, 5-deoxy-5-ethylthio-; 5-(Ethylthio)-5-deoxy-D-ribofuranose; 5-Ethylmercapto-5-deoxyribose; 5-ETHYLTHIORIBOSE; 5-Deoxy-5-(ethylthio)-D-ribose
EINECS	Contact for details

Quality Control

Our 5-S-Ethyl-5-Thioribose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.