Description

16-Doxyl-Stearic Acid is a spin-labeled derivative of stearic acid, incorporating a stable nitroxide radical (doxyl group) at the 16th carbon position. This unique structure makes it an essential tool in biophysical and materials research for probing molecular dynamics, membrane fluidity, and structural organization. It is primarily utilized by research scientists and product developers in the life sciences, advanced materials, and analytical chemistry sectors.

Application

• Membrane Biophysics Research: As a spin probe for Electron Paramagnetic Resonance (EPR) spectroscopy to study lipid bilayer fluidity, phase transitions, and protein-lipid interactions.
• Polymer Science: Investigating molecular mobility, free volume, and the microstructure of polymers and advanced materials.
• Antioxidant Studies: Serving as a model compound to study the behavior and efficacy of nitroxide-based radical scavengers.
• Model Lipid Systems: Incorporation into liposomes and micelles to create well-defined systems for spectroscopic analysis and drug delivery mechanism studies.
• Surface Chemistry: Used to functionalize surfaces and nanoparticles to study interfacial properties and molecular orientation.
• Diagnostic Reagent Development: A key intermediate in the synthesis of specialized reagents for clinical and research assays.

Basic Information

Product Name	16-Doxyl-Stearic Acid
CAS No.	53034-38-1
Molecular Formula	C24H46NO3
Molecular Weight	396.63 g/mol
Synonyms	16-DOXYL-stearic acid; 16-(4,4-Dimethyl-3-oxazolidinyloxy)stearic acid; 16-NS; 16-Nitroxide stearate; 2-(14-Carboxytetradecyl)-2-ethyl-4,4-dimethyl-3-oxazolidinyloxy; EPR Probe 16-doxyl-stearic acid; Stearic acid, 16-doxyl-; 16-DSA
EINECS	Contact for details

Quality Control

Our 16-Doxyl-Stearic Acid is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, critical for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and radical content. We adhere to relevant Good Manufacturing Practice (GMP) principles for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to the light-sensitive nature of the nitroxide radical, prolonged exposure to light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder or crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Nitroxide Radical Content	≥ 90%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.