Description

n-Formylcytisine is a high-purity alkaloid derivative, specifically the N-formylated analog of the natural product cytisine. This compound is a critical advanced pharmaceutical intermediate and a valuable research-grade reference standard for medicinal chemistry and pharmacological studies. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nicotinic acetylcholine receptor (nAChR) ligands and other pharmacologically active compounds.
• Reference Standard: Used as a certified standard in analytical laboratories for method development, validation, and quality control of related substances.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies targeting neurological pathways.
• Biochemical Research: Employed in in vitro studies to investigate receptor binding affinity and functional activity at nAChR subtypes.
• Process Development: Used in scaling up synthetic routes for the production of cytisine derivatives under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	n-Formylcytisine
CAS No.	53007-06-0
Molecular Formula	C12H15N3O2
Molecular Weight	233.27 g/mol
Synonyms	N-Formylcytisine; Cytisine N-formyl derivative; (-)-Cytisine formamide; 1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one, 3-formyl-; 3-Formyl-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
EINECS	Contact for details

Quality Control

Our n-Formylcytisine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis, identity confirmation (IR, NMR), and residual solvent screening to ensure it meets stringent specifications for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.