Description

p-Aminophenyl-n-Acetyl-B-D-Thioglucosami Nide is a specialized glycoside derivative with a reactive aromatic amine group, making it a valuable intermediate in synthetic organic chemistry. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and biochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutic agents and diagnostic probes.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel glycosidase inhibitors and targeted drug conjugates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for glycosidase and glycosyltransferase assays.
• Probe Development: Acts as a starting material for synthesizing fluorescent or affinity-labeled probes for cellular imaging and target identification.
• Glycoconjugate Synthesis: Employed in the chemical and chemoenzymatic preparation of complex oligosaccharides and glycopeptides.
• Library Synthesis: A valuable building block for creating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	p-Aminophenyl-n-Acetyl-B-D-Thioglucosami Nide
CAS No.	52722-51-7
Molecular Formula	C14H20N2O5S
Molecular Weight	328.38 g/mol
Synonyms	4-Aminophenyl 2-Acetamido-2-deoxy-1-thio-β-D-glucopyranoside; p-Aminophenyl 2-Acetamido-2-deoxy-1-thio-β-D-glucopyranoside; 1-Thio-β-D-N-acetylglucosaminide 4-aminophenyl; PNP-β-GlcNAc; 4-Nitrophenyl N-acetyl-β-D-thioglucosaminide (related precursor); 4-Aminophenyl N-acetyl-β-D-thioglucosaminide; NAG-thiophenyl-p-amine
EINECS	Contact for details

Quality Control

Our p-Aminophenyl-n-Acetyl-B-D-Thioglucosami Nide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.