Description

(2β,5α,12β,19α)-1-Demethyl-6β,7β-Epoxyvallesamidine is a complex, high-purity alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for developing novel bioactive molecules, particularly in the exploration of central nervous system (CNS) agents and other therapeutic areas. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on alkaloid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex natural product analogs and potential drug candidates.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies aimed at discovering new bioactive compounds with improved efficacy and safety profiles.
• Natural Product Synthesis: Employed in total synthesis projects to construct complex alkaloid frameworks found in nature.
• Biochemical Research: Utilized in studies investigating the interaction of alkaloid derivatives with biological targets such as receptors and enzymes.

Basic Information

Product Name	(2β,5α,12β,19α)-1-Demethyl-6β,7β-Epoxyvallesamidine
CAS No.	52659-54-8
Molecular Formula	C22H28N2O4
Molecular Weight	384.47 g/mol
Synonyms	1-Demethyl-6β,7β-epoxyvallesamidine; 19-Epi-1-demethyl-6β,7β-epoxyvallesamidine; Vallesamidine derivative; Alstonia scholaris alkaloid derivative; (2β,5α,12β,19α)-1-Demethyl-6,7-epoxyvallesamidine; 6β,7β-Epoxy-1-norvallesamidine; 1-Nor-6β,7β-epoxyvallesamidine
EINECS	Contact for details

Quality Control

Our (2β,5α,12β,19α)-1-Demethyl-6β,7β-Epoxyvallesamidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.