Description

Hemoglobin J Habana is a specific variant of hemoglobin, a vital oxygen-transporting metalloprotein found in red blood cells. This high-purity biochemical is essential for advanced research into hemoglobinopathies, oxygen-binding kinetics, and the development of diagnostic standards. It serves as a critical reagent for researchers and manufacturers in the fields of clinical diagnostics, hematology research, and biopharmaceutical development, where precise and consistent protein behavior is paramount.

Application

• Clinical Diagnostics & Calibration: Used as a reference standard and control material in assays for abnormal hemoglobin detection and quantification.
• Biomedical Research: Fundamental studies on hemoglobin structure-function relationships, oxygen affinity, and molecular pathology of hemoglobin variants.
• Hematology Studies: Investigation of sickle cell disease, thalassemias, and other hemoglobin-related disorders to understand disease mechanisms.
• Biochemical Reagent: Serves as a purified protein substrate in enzymatic studies, binding assays, and spectroscopic analysis.
• Pharmaceutical Development: Potential use in research for blood substitutes and oxygen-therapeutic agents.
• Educational & Quality Control: Employed in academic settings and by diagnostic kit manufacturers for training and internal quality assurance protocols.

Basic Information

Product Name	Hemoglobin J Habana
CAS No.	52337-02-7
Molecular Formula	C2952H4664N812O832S8Fe4
Molecular Weight	~64,500 Da (for α2β2 tetramer)
Synonyms	Hb J Habana; Hemoglobin variant J Habana; α-2 globin variant; HBA2 p.Glu47Lys; Hemoglobin α247(E5)Asp→Lys β2; Deoxyhemoglobin J Habana (if applicable); Oxyhemoglobin J Habana (if applicable)
EINECS	Contact for details

Quality Control

Our Hemoglobin J Habana is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot is subjected to a comprehensive suite of analytical tests, including purity assessment by HPLC, spectral analysis for correct heme environment, and functional oxygen-binding checks. A Certificate of Analysis (COA) detailing specific results for identity, purity, and stability is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / UV-Vis)	Conforms to standard for Hemoglobin J Habana
Purity (HPLC)	≥ 95% (by area)
Protein Content (Biuret)	≥ 90%
Methemoglobin Content	≤ 5%
Solubility	Clear solution in buffer
pH (in solution)	6.5 - 7.5
Biological Activity (O2 binding)	Retained activity confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.