Description

Fagaronine is a benzophenanthridine alkaloid of significant interest in pharmaceutical and biochemical research. This compound matters due to its potent biological activity, particularly its established role as a topoisomerase inhibitor, which makes it a valuable reference standard and a key intermediate in drug discovery programs. It is needed by research institutions, pharmaceutical developers, and contract manufacturing organizations (CMOs) focused on oncology, antiviral therapies, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control in drug manufacturing.
• Oncology Research: Serves as a critical biochemical tool for studying topoisomerase I and II inhibition mechanisms and screening for new anticancer agents.
• Antiviral Agent Development: Investigated for its potential activity against various viral targets in preclinical research settings.
• Biochemical Pathway Analysis: Employed in cell biology studies to induce apoptosis and analyze related cellular signaling pathways.
• Natural Product Synthesis: Acts as a key intermediate or target molecule in the total synthesis of complex alkaloids.
• Academic & Contract Research: Utilized in universities and CROs for fundamental pharmacological studies and client-specific research projects.

Basic Information

Product Name	Fagaronine
CAS No.	52259-65-1
Molecular Formula	C21H18NO4+
Molecular Weight	348.37 g/mol
Synonyms	Fagaronine; Fagaronin; NSC 157995; 8-Hydroxy-2,3,10-trimethoxybenzo[c]phenanthridin-7-ium; 7,8-Dihydro-2,3,10-trimethoxy-7-methylbenzo[c]phenanthridin-8-ol
EINECS	Contact for details

Quality Control

Our Fagaronine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.