Description

Betamethasone Acetate Phosphate is a synthetic glucocorticoid corticosteroid, specifically a phosphate ester prodrug of betamethasone acetate. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, offering enhanced water solubility for formulation versatility. It is a critical active pharmaceutical ingredient (API) and intermediate for manufacturers in the pharmaceutical and veterinary medicine sectors, particularly for injectable and topical preparations targeting severe inflammation and allergic conditions.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable corticosteroid formulations for systemic anti-inflammatory therapy.
• Topical Preparations: Used in creams, ointments, and lotions for treating severe dermatological conditions like psoriasis, eczema, and contact dermatitis.
• Veterinary Medicine: Employed in anti-inflammatory and anti-allergic treatments for companion animals and livestock.
• Ophthalmic Solutions: Component in eye drops and ointments for treating inflammatory eye disorders.
• Research & Development: Serves as a key reference standard and intermediate in steroid chemistry research and new drug development.
• Combination Therapies: Used in combination with other agents in complex formulations for enhanced therapeutic effect.

Basic Information

Product Name	Betamethasone Acetate Phosphate
CAS No.	52081-45-5
Molecular Formula	C26H34FO9P
Molecular Weight	540.52 g/mol
Synonyms	Betamethasone 21-Acetate 17-Phosphate; 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate 17-(dihydrogen phosphate); Betamethasone Acetate Sodium Phosphate (salt form); Betamethasone 17-Phosphate 21-Acetate; NSC-113019; U-67590A; BMAP; BAP
EINECS	Contact for details

Quality Control

Our Betamethasone Acetate Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for identity, purity, and impurities. We can support development with material meeting in-house pharmacopeial standards (USP/EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.