Description

Vanillylmandelic Acid Ethyl Ester is a key organic intermediate and reference standard of significant importance in analytical and synthetic chemistry. Its primary value lies in its role as a derivative of vanillylmandelic acid (VMA), a major catecholamine metabolite, making it crucial for research and diagnostic applications. This compound is essential for laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for the quantification of vanillylmandelic acid (VMA) in clinical diagnostics, particularly for neuroblastoma and pheochromocytoma screening.
• Biochemical Research: Serves as a critical intermediate in metabolic pathway studies and the synthesis of catecholamine analogs for neurological and endocrine research.
• Organic Synthesis: Acts as a versatile building block for the preparation of more complex molecules, including potential drug candidates and specialty fine chemicals.
• Diagnostic Kit Manufacturing: Incorporated into the production of enzyme-linked immunosorbent assay (ELISA) kits and other in-vitro diagnostic (IVD) reagents for accurate hormone metabolite detection.
• Quality Control: Employed by pharmaceutical QC laboratories to validate analytical methods, such as HPLC and GC-MS, for impurity profiling and assay development.

Basic Information

Product Name	Vanillylmandelic Acid Ethyl Ester
CAS No.	52058-11-4
Molecular Formula	C12H16O6
Molecular Weight	256.25 g/mol
Synonyms	VMA Ethyl Ester; 4-Hydroxy-3-methoxymandelic Acid Ethyl Ester; Ethyl 2-(4-Hydroxy-3-methoxyphenyl)-2-hydroxyacetate; Ethyl Vanillylmandelate; 3-Methoxy-4-hydroxymandelic Acid Ethyl Ester; HMMA Ethyl Ester; Ethyl (4-Hydroxy-3-methoxyphenyl)(hydroxy)acetate
EINECS	Contact for details

Quality Control

Our Vanillylmandelic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for use as a reference material. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.