Description

Aldosterone 21-Sulfate is a key sulfated metabolite of the mineralocorticoid hormone aldosterone. This compound is of significant value as a stable, high-purity reference standard and analytical reagent for precise biochemical research and diagnostic applications. It is primarily needed by pharmaceutical R&D laboratories, clinical diagnostic manufacturers, and academic institutions conducting studies in endocrinology, hypertension, and adrenal function.

Application

• Biochemical Research: Used as a critical reference standard in studies investigating the metabolism, transport, and physiological effects of aldosterone.
• Clinical Diagnostics: Serves as a calibrator and control in the development and validation of immunoassays (e.g., ELISA, RIA) and LC-MS/MS methods for quantifying aldosterone and its metabolites in biological samples.
• Pharmaceutical Development: Employed in pharmacokinetic and metabolic stability studies for drug candidates targeting the renin-angiotensin-aldosterone system (RAAS).
• Endocrinology Studies: Essential for research into disorders of adrenal function, such as primary aldosteronism (Conn's syndrome) and congenital adrenal hyperplasia.
• Quality Control: Acts as a purity standard for ensuring the quality of other related steroid compounds and diagnostic kits.

Basic Information

Product Name	Aldosterone 21-Sulfate
CAS No.	52036-29-0
Molecular Formula	C21H28O8S
Molecular Weight	440.51 g/mol
Synonyms	Aldosterone 21-Hemisulfate; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al 21-Sulfate; 18-Oxoaldosterone 21-Sulfate; Aldosterone Sulfate; Aldosterone 21-Monosulfate
EINECS	Contact for details

Quality Control

Our Aldosterone 21-Sulfate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.