Description

p-Nitrophenyl-B-L-Thio-Fucopyranoside is a specialized chromogenic substrate designed for the detection and study of specific glycosidase enzymes. This compound is critical for biochemical research and diagnostic applications where precise enzymatic activity measurement is required. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, enzymology, and diagnostic assay development.

Application

• Enzymatic Substrate for α-L-Fucosidase: Used as a specific chromogenic substrate to detect and quantify α-L-fucosidase activity in research and clinical diagnostics.
• Biochemical Research: Essential tool for studying enzyme kinetics, inhibition, and the role of fucosidases in various biological pathways.
• Diagnostic Kit Manufacturing: A key component in the formulation of diagnostic kits for lysosomal storage disorders, such as fucosidosis.
• High-Throughput Screening (HTS): Employed in drug discovery programs to identify potential inhibitors of fucosidase enzymes.
• Microbiology and Cell Biology: Used to probe glycosidase activity in microbial and mammalian cell systems.
• Quality Control in Biopharma: Acts as a reagent for monitoring the activity of enzyme preparations used in biopharmaceutical processes.

Basic Information

Product Name	p-Nitrophenyl-B-L-Thio-Fucopyranoside
CAS No.	51885-71-3
Molecular Formula	C16H21NO7S
Molecular Weight	371.41 g/mol
Synonyms	4-Nitrophenyl β-L-thiofucopyranoside; p-Nitrophenyl β-L-thiofucopyranoside; PNPTF; β-L-Thiofucopyranoside, 4-nitrophenyl; 4-Nitrophenyl 1-thio-β-L-fucopyranoside; 1-Thio-β-L-fucopyranoside 4-nitrophenyl ester; Substrate for α-L-Fucosidase
EINECS	Contact for details

Quality Control

Our p-Nitrophenyl-B-L-Thio-Fucopyranoside is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation (IR, NMR), and specific activity validation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Activity	Contact for details
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.