Description

Luteinizing Hormone-Releasing Hormone Fragment 6-10) is a biologically active pentapeptide fragment derived from the native Luteinizing Hormone-Releasing Hormone (LHRH). This compound is of significant value in biochemical and pharmaceutical research, particularly for studying the structure-activity relationships of neuroendocrine peptides. It serves as a critical intermediate and reference standard for researchers and manufacturers in the fields of endocrinology, peptide synthesis, and therapeutic development.

Application

• Biochemical Research: Used as a reference standard and intermediate in studies investigating the structure, function, and metabolism of Luteinizing Hormone-Releasing Hormone (LHRH/GnRH).
• Pharmaceutical Development: Serves as a key building block and analytical standard in the research and synthesis of peptide-based therapeutics targeting hormonal pathways.
• Endocrinology Studies: Employed in in vitro and in vivo assays to understand the regulation of gonadotropin secretion and reproductive biology.
• Peptide Synthesis: Acts as a crucial fragment for the solid-phase or solution-phase synthesis of longer, modified LHRH analogs for research purposes.
• Diagnostic Reagent Manufacturing: Utilized in the development and calibration of immunoassays and other diagnostic kits related to reproductive health.
• Academic & Institutional Research: A fundamental tool for universities and research institutes conducting advanced studies in neuroendocrinology and peptide chemistry.

Basic Information

Product Name	Luteinizing Hormone-Releasing Hormone Fragment 6-10)
CAS No.	51826-30-3
Molecular Formula	C27H44N10O8
Molecular Weight	636.71 g/mol
Synonyms	LHRH (6-10); GnRH Fragment (6-10); Luteinizing Hormone-Releasing Hormone (6-10); Luliberin (6-10); Gonadotropin-Releasing Hormone Fragment (6-10); Pyr-His-Trp-Ser-Tyr-OH; Pyroglutamyl-Histidyl-Tryptophyl-Seryl-Tyrosine; pGlu-His-Trp-Ser-Tyr
EINECS	Contact for details

Quality Control

Our Luteinizing Hormone-Releasing Hormone Fragment 6-10) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from HPLC, MS, and NMR characterization. Our quality commitment aligns with the standards expected for research-grade biochemicals, supporting reproducible and reliable scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep containers sealed under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.