Description

H-Asp-Arg-β-Na is a specialized dipeptide derivative, specifically the sodium salt of the aspartyl-arginine β-naphthylamide. This compound is a critical biochemical reagent valued for its role as a selective and sensitive substrate for enzymatic assays. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in protease and peptidase research, particularly for the study of enzymes like trypsin and other arginine-specific proteases. The product's defined structure ensures consistent and reliable performance in high-throughput screening and diagnostic applications.

Application

• Enzymatic Substrate for Protease Research: Serves as a key chromogenic or fluorogenic substrate for the detection and kinetic study of trypsin-like serine proteases and other arginine-cleaving enzymes.
• Diagnostic Kit Manufacturing: Used in the formulation of in vitro diagnostic (IVD) kits for clinical laboratories to measure specific protease activity in biological samples.
• Biochemical Assay Development: Essential for developing and validating high-sensitivity assays in drug discovery pipelines, particularly for target identification and inhibitor screening.
• Academic and Pharmaceutical R&D: Supports fundamental research in biochemistry, cell biology, and medicinal chemistry for understanding proteolytic pathways.
• Quality Control in Biologics: Can be employed in purity and activity testing of enzyme preparations used in therapeutic manufacturing processes.

Basic Information

Product Name	H-Asp-Arg-β-Na
CAS No.	51528-58-6
Molecular Formula	C₂₀H₂₇N₆O₆•xNa
Molecular Weight	458.47 g/mol (Free acid)
Synonyms	L-Aspartyl-L-arginine β-naphthylamide sodium salt; Asp-Arg-βNA; Nα-(Nα-Benzoyl-L-arginyl)-L-aspartic acid β-naphthylamide sodium salt; Bz-Arg-Asp-βNA-Na; Trypsin substrate (β-naphthylamide); H-Asp-Arg-2-Naphthylamide sodium salt; Bz-R-D-βNA Na+; 51528-58-6
EINECS	Contact for details

Quality Control

Our H-Asp-Arg-β-Na is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) detailing batch-specific results for assay, impurities, and physical characteristics are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.