Description

Ketodextran Oxime is a specialized chemical derivative of dextran, characterized by the introduction of ketone and oxime functional groups. This modification is significant as it enhances the molecule's reactivity and conjugation capabilities, making it a valuable intermediate for advanced bioconjugation and polymer chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biomedical, and diagnostic sectors for applications such as drug delivery system development and the synthesis of functionalized polymers.

Application

• Bioconjugation Linker: Serves as a reactive intermediate for attaching drugs, proteins, or fluorescent probes to dextran-based carriers.
• Polymer Modification: Used to introduce functional handles onto dextran backbones for creating smart hydrogels or responsive materials.
• Drug Delivery Systems: A key building block in the development of targeted and controlled-release nanoparticle formulations.
• Diagnostic Reagents: Employed in the synthesis of contrast agents or labeled compounds for imaging and assay development.
• Biomaterial Functionalization: Enhances the surface properties of scaffolds and matrices for tissue engineering applications.
• Research & Development: A critical reagent in academic and industrial R&D for exploring new macromolecular architectures and bio-interfaces.

Basic Information

Product Name	Ketodextran Oxime
CAS No.	51194-97-9
Molecular Formula	Contact for details
Molecular Weight	Varies (Dextran-based polymer)
Synonyms	Dextran ketoxime; Oximated ketodextran; Dextran, ketone oxime derivative; Ketone-functionalized dextran oxime; Dextran keto-oxime; Reactive dextran derivative; CAS 51194-97-9
EINECS	Contact for details

Quality Control

Our Ketodextran Oxime is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure consistent purity, functionality, and molecular weight distribution. Certificates of Analysis (COA) detailing key parameters such as degree of substitution, oxime content, and residual solvents are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Oxime Content)	≥ 85% (or as per grade)
Degree of Substitution (Ketone)	Specified range per grade
Molecular Weight (Average)	Specified range (e.g., 10kDa, 40kDa, 70kDa)
Solubility	Soluble in water, DMSO
Residual Moisture (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.