Description

(12R,15R)-12,15-Epoxy-1α,2,15,20-Tetrahydro-16A-Homo-21-Norsenecionan-11,16A-Dione is a complex, high-purity organic compound with the CAS registry number 50906-96-2. This specialized intermediate is valued for its unique stereochemistry and functional groups, which make it a critical building block in advanced synthetic pathways. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of novel bioactive molecules and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex therapeutic agents.
• Organic Synthesis Research: Used as a sophisticated building block in academic and industrial laboratories for constructing complex polycyclic frameworks and studying novel chemical transformations.
• Natural Product Analog Synthesis: Employed in the semi-synthesis or total synthesis of analogs related to senecionine alkaloids for structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Utilized in the development of specialized molecular probes to investigate biological pathways and enzyme interactions.
• Process Chemistry Development: Acts as a critical intermediate for scaling up synthetic routes in process chemistry, requiring high purity and consistent quality.

Basic Information

Item	Details
Product Name	(12R,15R)-12,15-Epoxy-1α,2,15,20-Tetrahydro-16A-Homo-21-Norsenecionan-11,16A-Dione
CAS No.	50906-96-2
Molecular Formula	C18H25NO4
Molecular Weight	319.40 g/mol
Synonyms	12,15-Epoxy-1α,2,15,20-tetrahydro-16a-homo-21-norsenecionan-11,16a-dione; (12R,15R)-12,15-Epoxy-1α,2,15,20-tetrahydro-16a-homo-21-norsenecionan-11,16a-dione; 16a-Homo-21-norsenecionan-11,16a-dione, 12,15-epoxy-1α,2,15,20-tetrahydro-, (12R,15R)-; A derivative of senecionine alkaloid; Pyrrolizidine alkaloid intermediate; Complex polycyclic diketone.
EINECS	Contact for details

Quality Control

Every batch of (12R,15R)-12,15-Epoxy-1α,2,15,20-Tetrahydro-16A-Homo-21-Norsenecionan-11,16A-Dione is manufactured and tested under a strict Quality Management System. We provide comprehensive analytical data to ensure identity, purity, and consistency, which is critical for research and development applications. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and optical rotation is supplied with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and prolonged exposure to air; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.