Description

Disodium Protoporphyrin Ix is a water-soluble salt form of protoporphyrin IX, a key intermediate in the heme biosynthetic pathway. This high-purity compound is essential for research and development in photodynamic therapy (PDT), serving as a crucial precursor for photosensitizer synthesis. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions studying porphyrin chemistry and cellular metabolism.

Application

• Photodynamic Therapy (PDT) Research: As a direct precursor for the synthesis and study of various photosensitizing agents used in cancer treatment and antimicrobial applications.
• Biochemical Research: Used in studies of heme biosynthesis, porphyrin metabolism, and associated disorders like porphyrias.
• Diagnostic Reagents: Employed in the development of clinical diagnostic kits and assays for measuring enzymes like ferrochelatase or for heme-related metabolic profiling.
• Cell Biology Studies: Utilized as a fluorescent probe for mitochondrial labeling and visualization in live-cell imaging due to its natural accumulation in mitochondria.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical manufacturing and academic research.
• Material Science: Investigated for use in the development of organic semiconductors and light-harvesting materials due to its porphyrin structure.

Basic Information

Product Name	Disodium Protoporphyrin Ix
CAS No.	50865-01-5
Molecular Formula	C34H32N4Na2O4
Molecular Weight	606.62 g/mol
Synonyms	Protoporphyrin IX Disodium Salt; PpIX Disodium Salt; Disodium 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionate; 2,18-Bis(2-carboxyethyl)-8,13-divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid disodium salt; Hematoporphyrin IX Disodium Salt (related); Photofrin precursor; PDT Intermediate; Heme precursor salt.
EINECS	Contact for details

Quality Control

Our Disodium Protoporphyrin Ix is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometry for identification, and residual solvent analysis, to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under subdued light. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	Dark red to purple-brown powder
Identification (HPLC/UV-Vis)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0 %
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
pH (1% Solution)	7.0 - 9.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.