Description

trans-Cinnamoylcocaine is a specialized cocaine alkaloid derivative, distinguished by the presence of a cinnamoyl ester group. This compound is of significant interest in forensic science, analytical chemistry, and pharmacological research for its role as a reference standard and a metabolite of cocaine. It serves as a critical material for researchers and laboratories requiring high-purity analytical markers. Key industrial users include forensic laboratories, pharmaceutical R&D facilities, and chemical manufacturers engaged in the synthesis of controlled substance analogs for legal and scientific purposes.

Application

• Forensic Reference Standard: Primary application as a certified reference material (CRM) for the identification and quantification of cocaine and its metabolites in forensic toxicology and law enforcement analysis.
• Pharmacological Research: Used in biochemical and pharmacological studies to investigate the metabolism, pharmacokinetics, and structure-activity relationships (SAR) of cocaine analogs.
• Analytical Method Development: Serves as a critical component in developing and validating analytical methods, such as HPLC, GC-MS, and LC-MS/MS, for drug testing and impurity profiling.
• Chemical Synthesis Intermediate: Employed as a key intermediate or precursor in the controlled synthesis of other tropane alkaloid derivatives for research purposes.
• Quality Control & Assurance: Utilized by pharmaceutical and chemical manufacturers to calibrate equipment and verify the purity of related substances in compliance with regulatory guidelines.

Basic Information

Product Name	trans-Cinnamoylcocaine
CAS No.	50763-20-7
Molecular Formula	C25H27NO4
Molecular Weight	405.49 g/mol
Synonyms	Cocaine cinnamate; 3β-Benzoyloxy-2β-(trans-cinnamoyloxy)tropane; trans-Cinnamoylcocaine; (1R,2R,3S,5S)-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid (2E)-3-phenyl-2-propen-1-yl ester; Cinnamoylcocaine; Cocaine, cinnamate (ester)
EINECS	Contact for details

Quality Control

Our trans-Cinnamoylcocaine is produced and handled under strict quality management protocols to ensure the highest standards of purity and traceability required for research and analytical applications. Each batch is subjected to comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A detailed Certificate of Analysis (COA) is provided, documenting the results against stringent internal specifications. We adhere to relevant guidelines for the handling of controlled substance analogs to ensure regulatory compliance for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container securely sealed to protect from moisture and contamination. Store in accordance with all applicable local and international regulations for controlled substance precursors or analogs.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.