Description

Aza-ε-Atp is a specialized purine nucleoside analog with significant biochemical research applications. This compound is valued for its role as a potent and selective inhibitor of specific kinase and ATPase enzymes, making it a critical tool for probing cellular signaling pathways and energy metabolism. It is primarily utilized by research institutions and pharmaceutical developers in the fields of enzymology, cancer research, and metabolic disorder studies.

Application

• Biochemical Research: Serves as a key inhibitor in enzymatic studies to investigate ATP-binding sites and kinase activity.
• Cancer Research: Used in vitro to study the effects of ATP-competitive inhibitors on tumor cell proliferation and survival pathways.
• Signal Transduction Studies: A vital tool for dissecting complex phosphorylation cascades and intracellular communication networks.
• Metabolic Pathway Analysis: Employed to study cellular energy homeostasis and the role of specific ATPases in metabolic diseases.
• Drug Discovery & Development: Acts as a reference compound or lead structure in high-throughput screening for novel therapeutic agents.
• Academic & Pharmaceutical R&D: Essential for basic research in university labs and for target validation in pre-clinical drug development pipelines.

Basic Information

Item	Detail
Product Name	Aza-ε-Atp
CAS No.	50663-89-3
Molecular Formula	C11H15N6O12P3
Molecular Weight	540.17 g/mol
Synonyms	1-Aza-ε-ATP; ε-1-Azaadenosine 5'-triphosphate; ε-Aza-ATP; 1-Deaza-ε-ATP; ε-ATP analog; Adenosine 5'-(tetrahydrogen triphosphate), 1-aza-ε-derivative; ATP ε-aza analog
EINECS	Contact for details

Quality Control

Our Aza-ε-Atp is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.