Description

[13S,13Ar,(+)]-5,8,13,13A-Tetrahydro-2,9-Dimethoxy-13-Methyl-6H-Dibenzo[A,G]Quinolizine-3,10-Diol is a high-purity, complex isoquinoline alkaloid derivative, identified by CAS number 50656-80-9. This compound is valued for its specific stereochemistry and functional groups, making it a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of potential therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate receptor interactions and enzyme inhibition related to its alkaloid core structure.
• Asymmetric Synthesis: Employed as a sophisticated starting material or ligand precursor in catalytic asymmetric reactions due to its rigid, polycyclic framework.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals, dyes, and advanced materials requiring a complex isoquinoline backbone.
• Academic Research: Utilized in university and institutional labs for methodological development in total synthesis and natural product chemistry.

Basic Information

Item	Details
Product Name	[13S,13Ar,(+)]-5,8,13,13A-Tetrahydro-2,9-Dimethoxy-13-Methyl-6H-Dibenzo[A,G]Quinolizine-3,10-Diol
CAS No.	50656-80-9
Molecular Formula	C20H23NO4
Molecular Weight	341.40 g/mol
Synonyms	(+)-Corytuberine; (13S,13aR)-5,8,13,13a-Tetrahydro-2,9-dimethoxy-13-methyl-6H-dibenzo[a,g]quinolizine-3,10-diol; 3,10-Dihydroxy-2,9-dimethoxy-13-methyl-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine; Corytuberine; L-Corytuberine
EINECS	Contact for details

Quality Control

Our [13S,13Ar,(+)]-5,8,13,13A-Tetrahydro-2,9-Dimethoxy-13-Methyl-6H-Dibenzo[A,G]Quinolizine-3,10-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.