Description

8-Benzylthioadenosine-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified, cell-permeable analog of cyclic adenosine monophosphate (cAMP), designed for enhanced stability and biological activity. This compound is a critical research tool for studying intracellular signaling pathways, particularly those mediated by protein kinase A (PKA). It is primarily utilized by researchers and developers in the fields of pharmacology, biochemistry, and cell biology for investigating cellular regulation, signal transduction, and as a potential lead compound in drug discovery.

Application

• Biochemical Research: As a potent and stable activator of Protein Kinase A (PKA) for studying cAMP-dependent signaling pathways in vitro and in cell-based assays.
• Cell Biology Studies: Investigation of cellular processes such as gene expression, metabolism, ion channel function, and cell proliferation/differentiation.
• Pharmacological Tool: Used to elucidate the role of cAMP in disease models, aiding in the validation of therapeutic targets for conditions like heart failure, inflammation, and neurological disorders.
• Drug Discovery & Development: Serves as a reference standard and a key intermediate in the synthesis of novel therapeutic agents targeting PKA and related pathways.
• Academic & Institutional Research: Fundamental research in universities and institutes focused on intracellular communication and second messenger systems.

Basic Information

Product Name	8-Benzylthioadenosine-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	50655-17-9
Molecular Formula	C17H18N5O6PSNa
Molecular Weight	497.38 g/mol
Synonyms	8-Benzylthio-cAMP sodium salt; 8-BnT-cAMP sodium salt; 8-Benzylthioadenosine cyclic 3',5'-(hydrogen phosphate) sodium salt; 8-(Benzylthio)adenosine-3',5'-cyclic monophosphate sodium salt; Bt-cAMP sodium salt; 8-BnT-cyclic AMP sodium salt; cAMP, 8-benzylthio-, sodium salt
EINECS	Contact for details

Quality Control

Our 8-Benzylthioadenosine-3',5'-Cyclic Monophosphate Sodium Salt is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the rigorous requirements of the research and pharmaceutical development communities.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.