Description

p-Nitrophenyl 2-Acetamido-2-Deoxy-α-D-Galactopyranoside is a specialized chromogenic substrate used in enzymatic assays. This compound is critical for the detection and quantification of α-N-acetylgalactosaminidase and related glycosidase enzymes. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science research sectors for biochemical analysis and diagnostic kit development.

Application

• Enzymatic Substrate for α-N-Acetylgalactosaminidase: A key chromogenic reagent for the specific detection and activity measurement of α-NAGA enzymes in research and clinical diagnostics.
• Diagnostic Kit Manufacturing: Used as a core component in the production of diagnostic kits for genetic disorders like Schindler/Kanzaki disease.
• Biochemical Research: Essential for studying glycosidase enzyme kinetics, inhibition, and function in various metabolic pathways.
• Quality Control in Biopharma: Employed in purity and activity testing of enzyme preparations within biopharmaceutical manufacturing processes.
• High-Throughput Screening (HTS): Suitable for use in automated HTS platforms to identify potential therapeutic modulators of glycosidase activity.

Basic Information

Product Name	p-Nitrophenyl 2-Acetamido-2-Deoxy-α-D-Galactopyranoside
CAS No.	50645-66-4
Molecular Formula	C14H18N2O8
Molecular Weight	342.30 g/mol
Synonyms	4-Nitrophenyl N-acetyl-α-D-galactosaminide; p-Nitrophenyl α-D-GalNAc; PNP-α-GalNAc; 4-Nitrophenyl 2-acetamido-2-deoxy-α-D-galactopyranoside; α-PNP-GalNAc; N-Acetyl-α-D-galactosaminide 4-nitrophenyl; 2-Acetamido-2-deoxy-α-D-galactopyranosyl 4-nitrophenyl ether
EINECS	Contact for details

Quality Control

Our p-Nitrophenyl 2-Acetamido-2-Deoxy-α-D-Galactopyranoside is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive enzymatic assays and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.