Description

(+)-1 4-Di-o-Tosyl-D-Threitol CAS NO 50623-73-9 is a high-purity chiral building block and protecting group reagent of significant importance in asymmetric synthesis. This compound is valued for its role in the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to induce stereoselectivity in key bond-forming reactions.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates and APIs.
• Protecting Group Reagent: Employed for the selective protection of diol functionalities in complex multi-step syntheses.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and medicinal chemistry laboratories.
• Fine Chemical Production: Applied in the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(+)-1,4-Di-o-Tosyl-D-Threitol
CAS No.	50623-73-9
Molecular Formula	C20H26O8S2
Molecular Weight	466.55 g/mol
Synonyms	D-Threitol 1,4-Di-p-toluenesulfonate; (2R,3S)-1,4-Bis[(4-methylphenyl)sulfonyloxy]butane-2,3-diol; 1,4-Di-O-tosyl-D-threitol; D-1,4-Ditosylthreitol; (+)-1,4-Di-O-tosyl-D-threitol; DTDT; (2R,3S)-1,4-Bis(tosyloxy)butane-2,3-diol
EINECS	Contact for details

Quality Control

Our (+)-1,4-Di-o-Tosyl-D-Threitol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality system is designed to meet the rigorous standards expected in pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.