Description

7,8-Didehydro-4,5α-Epoxy-3-Methoxymorphinan-6α-Yl β-D-Glucopyranosiduronic Acid is a high-purity, specialized chemical intermediate of significant interest in advanced pharmaceutical research and development. This compound, identified by CAS number 50444-03-6, is a key metabolite and reference standard for the study of specific opioid pathways and their biochemical interactions. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in the synthesis, metabolism, and quality control of complex therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for the quantitative and qualitative analysis of drug metabolites in compliance with regulatory guidelines.
• Metabolite Research: Used in preclinical and clinical studies to investigate the metabolic pathways, pharmacokinetics, and pharmacodynamics of related morphinan-derived pharmaceuticals.
• Analytical Method Development: Essential for developing and validating sensitive analytical methods, such as HPLC-MS/MS, in bioanalytical and forensic toxicology laboratories.
• Impurity Profiling: Employed as a marker for identifying and quantifying process-related impurities or degradation products in active pharmaceutical ingredient (API) manufacturing.
• Biochemical Research: Acts as a tool compound in biochemical assays to study enzyme interactions, receptor binding, and other molecular mechanisms.

Basic Information

Product Name	7,8-Didehydro-4,5α-Epoxy-3-Methoxymorphinan-6α-Yl β-D-Glucopyranosiduronic Acid
CAS No.	50444-03-6
Molecular Formula	C25H29NO10
Molecular Weight	503.50 g/mol
Synonyms	Morphine-6-glucuronide; M6G; Morphine 6-β-D-glucuronide; 6-Glucuronylmorphine; 6-Mono-glucuronylmorphine; 4,5α-Epoxy-17-methyl-7,8-didehydro-3,6α-dihydroxy-morphinan-6α-yl β-D-glucopyranosiduronic acid; 7,8-Didehydro-4,5α-epoxy-17-methylmorphinan-3,6α-diol 6α-(β-D-glucuronide)
EINECS	Contact for details

Quality Control

Our 7,8-Didehydro-4,5α-Epoxy-3-Methoxymorphinan-6α-Yl β-D-Glucopyranosiduronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research and development. Comprehensive Certificates of Analysis (COA) detailing purity, chromatographic data, and other critical parameters are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.